Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
Author
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Morales Montecinos, Javier
Author
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Sepúlveda Rivas, Sabrina
Author
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Oyarzún Ampuero, Felipe
Author
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Lavandero González, Sergio
Author
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Kogan Bocian, Marcelo
Admission date
dc.date.accessioned
2015-12-17T02:05:21Z
Available date
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2015-12-17T02:05:21Z
Publication date
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2015
Cita de ítem
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Current Pharmaceutical Design Volumen: 21 Número: 29 Páginas: 4276-4284
en_US
Identifier
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1381-6128
Identifier
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DOI: 10.2174/1381612821666150901103556
Identifier
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https://repositorio.uchile.cl/handle/2250/135800
General note
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Artículo de publicación ISI
en_US
General note
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Sin acceso a texto completo
Abstract
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Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have
shown recent success. Both intravenous and oral administration have been investigated and
achieved different degrees of development. While circulating polymeric nanostructured carriers are
subjected to a number of interactions, smart nanoparticle design has enabled the formulation of
active molecules to be delivered to specific targets for cardiovascular effects. This review aims at
outlining the multiple factors that can affect the fate of polymeric nanostructured carriers in systemic
circulation. With an understanding of these factors, the literature on the various polymeric
nanostructured carriers is reviewed. Finally, the emerging uses of nanotechnology to formulate
orally administered drugs for cardiovascular diseases are depicted