Show simple item record

Authordc.contributor.authorVillarroel Quintana, Claudio 
Authordc.contributor.authorLópez, Patricia 
Authordc.contributor.authorMerino Osorio, Paulina 
Authordc.contributor.authorIñíguez Vila, Germán 
Authordc.contributor.authorSir Petermann, Teresa 
Authordc.contributor.authorCodner Dujovne, Ethel 
Admission datedc.date.accessioned2016-05-09T18:38:15Z
Available datedc.date.available2016-05-09T18:38:15Z
Publication datedc.date.issued2015
Cita de ítemdc.identifier.citationGynecological Endocrinology Volumen: 31 Número: 8 Páginas: 625-629 (2015)en_US
Identifierdc.identifier.otherDOI: 10.3109/09513590.2015.1025380
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/138199
General notedc.descriptionArtículo de publicación ISIen_US
General notedc.descriptionSin acceso a texto completo
Abstractdc.description.abstractWe evaluated the association of hirsutism and oligomenorrhea (persistent menstrual cycles > 45 days) as screening criteria for the detection of biochemical hyperandrogenism (BH) and polycystic ovaries (PCOM) during adolescence and determined which androgens, granulosa cell hormone, ultrasonographic parameters have the best association with polycystic ovary syndrome (PCOS). Hirsute girls with oligomenorrhea (N = 26 Hirs/Oligo group) and non-hirsute girls with regular cycles (N = 63, C group) were studied. Prevalence of BH and PCOM, diagnostic performance of androgens and ultrasound parameters for PCOS diagnosis were analyzed. BH and PCOM prevalence were higher in the Hirs/Oligo girls than in the C girls (76.9% versus 25.5%; 92.3% versus 33.3%, respectively; p<0.0001). A complete PCOS phenotype (Hirs/Oligo with BH and PCOM) was observed in 73.1% of the Hirs/Oligo group. The presence of both BH and PCOM was observed in 7.9% of the C group. The parameters with the best diagnostic performance were free androgen index >= 6.1, testosterone >= 2.4 nmol/L, follicle number >= 12 and ovarian volume >= 10 ml anti-Mullerian hormone (AMH) exhibited a low diagnostic accuracy. Hirsutism and persistent menstrual cycle over 45 days are highly associated with BH and PCOM suggesting that the presences of both criteria are necessary for the diagnosis of PCOS during adolescence.en_US
Patrocinadordc.description.sponsorshipFONDECYT 1100123en_US
Lenguagedc.language.isoenen_US
Publisherdc.publisherTaylor & Francisen_US
Keywordsdc.subjectOligomenorreaen_US
Keywordsdc.subjectHirsutismoen_US
Keywordsdc.subjecten_US
Keywordsdc.subjecten_US
Keywordsdc.subjectSíndrome de ovario poliquístico--En adolescenciaen_US
Títulodc.titleHirsutism and oligomenorrhea are appropriate screening criteria for polycystic ovary syndrome in adolescentsen_US
Document typedc.typeArtículo de revista


Files in this item

Icon

This item appears in the following Collection(s)

Show simple item record