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Authordc.contributor.authorCarrillo, Ileana 
Authordc.contributor.authorCastillo, Christian 
Authordc.contributor.authorDroguett, Daniel 
Authordc.contributor.authorMuñoz, Lorena 
Authordc.contributor.authorLiempi, Ana 
Authordc.contributor.authorMaya Arango, Juan 
Authordc.contributor.authorGalanti Garrone, Norbel 
Authordc.contributor.authorKemmerling Weis, Ulrike 
Admission datedc.date.accessioned2017-03-02T14:01:49Z
Available datedc.date.available2017-03-02T14:01:49Z
Publication datedc.date.issued2016
Cita de ítemdc.identifier.citationPlacenta. Volumen: 45 Páginas: 95-95 Abstract de reunión: P1.75es_ES
Identifierdc.identifier.issn1532-3102
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/142932
Abstractdc.description.abstractCongenital Chagas’ disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi), which is able to cross the placental barrier and infect both the placenta and fetus. However, congenital transmission rates are low, suggesting the presence of local defense mechanisms. The trophoblast is the first tissue of the placental barrier in contact with the maternal blood; its epithelial turnover is considered part of innate immune system. Previous studies have shown that T. cruzi induces proliferation, differentiation and apoptosis in the trophoblast, suggesting an increase in epithelial turnover. Caspase 8 is an essential molecule not only during apoptotic cell death but also during trophoblast differentiation.es_ES
Lenguagedc.language.isoenes_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Sourcedc.sourcePlacentaes_ES
Títulodc.titleCaspase 8 inhibition increases the infection with trypanosoma cruzi in thehuman trophoblast cell line (bewo)es_ES
Document typedc.typeArtículo de revistaes_ES
Catalogueruchile.catalogadorC. R. B.es_ES
Indexationuchile.indexArtículo de publicación ISIes_ES


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile