Size at birth, infant, early and later childhood growth and adult body composition: a prospective study in a stunted population
Author
dc.contributor.author
Corvalán Aguilar, Camila
Author
dc.contributor.author
Gregory, C. O.
Author
dc.contributor.author
Ramírez Zea, M.
Author
dc.contributor.author
Martorell, R .
Author
dc.contributor.author
Stein, A. D
Admission date
dc.date.accessioned
2017-09-29T14:46:44Z
Available date
dc.date.available
2017-09-29T14:46:44Z
Publication date
dc.date.issued
2007
Cita de ítem
dc.identifier.citation
International Journal of Epidemiology 2007;36:550–557
es_ES
Identifier
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10.1093/ije/dym010
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/145125
Abstract
dc.description.abstract
Background Pre-natal and post-natal growth are associated with adult body composition,
but the relative importance of growth in different periods of childhood is still
unclear, particularly in stunted populations.
Methods We studied 358 women and 352 men measured as children in 1969–77 in
four villages in Guatemala, and re-measured as adults in 2002–04 (mean age
32.7 years). We determined the associations of body mass index (BMI) and
length at birth, and changes in BMI and length during infancy (0–1.0 year) and
early (1.0–3.0 years) and later (3.0–7.0 years) childhood, with adult BMI (aBMI),
percentage of body fat (aPBF), abdominal circumference (aAC) and fat-free mass
(aFFM).
Results Prevalence of stunting was high (64% at 3 years; HAZ< 2SD). Obesity
(WHZ>2SD) prevalence in childhood was <2%, while overweight prevalence in
adulthood was 52%. BMI at birth was positively associated with aBMI and aFFM
while length at birth was positively associated with aAC and aFFM. Increased
BMI in infancy and later childhood were positively associated with all four adult
body composition measures; associations in later childhood with fatness and
abdominal fatness were stronger than those with aFFM. Change in length
during infancy and early childhood was positively associated with all four adult
body composition outcomes; the associations with aFFM were stronger than
those with fat mass.
Conclusions Increases in BMI between 3.0 and 7.0 years had stronger associations with adult
fat mass and abdominal fat than with aFFM; increases in length prior to age
3.0 years were most strongly associated with increases in aFFM.