Facile synthesis of lithium carbonate nanoparticles with potential properties for bone repair applications
Author
dc.contributor.author
Covarrubias Gallardo, Cristián
Author
dc.contributor.author
Durán, Juan Pablo
Author
dc.contributor.author
Maureira, Miguel
Admission date
dc.date.accessioned
2018-07-17T16:41:08Z
Available date
dc.date.available
2018-07-17T16:41:08Z
Publication date
dc.date.issued
2018
Cita de ítem
dc.identifier.citation
Materials Letters 219 (2018) 205–208
es_ES
Identifier
dc.identifier.other
https://doi.org/10.1016/j.matlet.2018.02.075
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/149935
Abstract
dc.description.abstract
Lithium carbonate nanoparticles were synthesized by facile chemical route in the presence of organic
capping agents. Nanosized Li2CO3 particles of 86 nm in size were produced from LiOH solution and
preferably using PVA as a capping agent. FTIR-ATR analysis revealed that Li2CO3 phase is formed during
calcination of the freeze-dried synthesis product. In vitro tests shown that nanoparticle concentrations up
to 600 mg/mL do not disturb cell viability and promote the osteogenic differentiation of stem cells by Li+
ions (9.7 mM) leached from the nanoparticle. The biological properties exhibited by the Li2CO3
nanoparticles make of them attractive for bone repair applications.
es_ES
Patrocinador
dc.description.sponsorship
Academic Productivity Support
Program, U-Redes Consolidación 2017; University of Chile