First description of echinococcus ortleppi and cystic echinococcosis infection status in Chile
Author
dc.contributor.author
Correa, Felipe
Author
dc.contributor.author
Stoore, Caroll
Author
dc.contributor.author
Horlacher, Pamina
Author
dc.contributor.author
Jiménez, Mauricio
Author
dc.contributor.author
Hidalgo, Christian
Author
dc.contributor.author
Rojas, Cristian A.
Author
dc.contributor.author
Barros, Guilherme Figueiredo
Author
dc.contributor.author
Ferreira, Henrique Bunselmeyer
Author
dc.contributor.author
Hernández, Marcela
Author
dc.contributor.author
Navarro Cabrera, Gonzalo
Author
dc.contributor.author
Paredes, Rodolfo
Admission date
dc.date.accessioned
2018-09-27T19:01:33Z
Available date
dc.date.available
2018-09-27T19:01:33Z
Publication date
dc.date.issued
2018-05-17
Cita de ítem
dc.identifier.citation
Plos one Volumen: 13 Número: 5 Número de artículo: e0197620
es_ES
Identifier
dc.identifier.other
10.1371/journal.pone.0197620
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/151807
Abstract
dc.description.abstract
Cystic echinococcosis (CE), a parasitic disease caused by the cestode Echinococcus granulosus sensu lato (s.l.), is a worldwide zoonotic infection. Although endemic in Chile, information on the molecular characteristics of CE in livestock remains scarce. Therefore we aimed to describe the status of infection with E. granulosus s.l. in cattle from central Chile and also to contribute to the study of the molecular epidemiology of this parasite. According to our results, the prevalence of CE is 18.84% in cattle, similar to previous reports from Chile, suggesting that the prevalence in Santiago Metropolitan area has not changed in the last 30 years. Most of the cysts were found only in lungs (51%), followed by concurrent infection in liver and lungs (30%), and only liver (19%). Molecular characterization of the genetic diversity and population structure of E. granulosus s.l. from cattle in central Chile was performed using a section of the cytochrome c oxidase subunit 1 (cox1) mitochondrial gene. E. granulosus sensu stricto (s.s.) (G1-G3 genotypes) was confirmed by RFLP-PCR to be the dominant species affecting cattle (284 samples/290 samples); we also report for the first time in Chile the presence of E. ortleppi (G5 genotype) (2 samples/61 samples). The Chilean E. granulosus s.s. parsimony network displayed 1 main haplotype. Additional studies using isolates from many locations across Chile and different intermediate hosts will provide more data on the molecular structure of E. granulosus s.s. within this region. Likewise, investigations of the importance of E. ortleppi in human infection in Chile deserve future attention.
es_ES
Patrocinador
dc.description.sponsorship
Fondecyt-Chile
1161475
Universidad Andres Bello
DI-1398-16/I
DI-1249-16/RG
CNPq (Brazil)/CONICYT (Chile)
490.923/2008-9