Ultrasound characterization of cutaneous ulcers in systemic sclerosis
Author
dc.contributor.author
Suliman, Yossra A.
Author
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Kafaja, Suzanne
Author
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Fitzgerald, John
Author
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Wortsman, Ximena
Author
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Grotts, Jonathan
Author
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Matucci-Cerrinic, Marco
Author
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Ranganath, Veena K.
Author
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Furst, Daniel E.
Admission date
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2018-10-01T14:28:58Z
Available date
dc.date.available
2018-10-01T14:28:58Z
Publication date
dc.date.issued
2018-06
Cita de ítem
dc.identifier.citation
Clinical Rheumatology (2018) 37:1555–1561
es_ES
Identifier
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10.1007/s10067-018-3986-5
Identifier
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https://repositorio.uchile.cl/handle/2250/151876
Abstract
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Skin ulcers in scleroderma (SSc) patients are considered a major challenge, both in clinical assessment and treatment decisions. The objective of our study is to assess ultrasonographic (US) morphology of skin ulcers in SSc patients and evaluate if US will be of value in enhancing our clinical information and influence our management plans. We examined a convenience sample of 21 skin ulcers reported in 10 SSc patients by US. We used a previously published US definition of normal skin and developed a preliminary US definition of skin ulcer. Skin ulcers were evaluated by gray scale (GS) and power Doppler (PD) and separated into ulcer and non-ulcer lesions; pain and ulcer measures were obtained using visual analogue scales (VAS). Lesions were characterized and ulcers were clinically and sonographically measured. Ten patients presenting with 21 skin lesions were examined by US. Applying our US definition of skin ulcer, all ulcers were available to measure by ultrasound. Eight lesions were sonographically defined as ulcers, and 13 lesions as non-ulcer lesions. Three ulcers had high PD signals suggestive of infection requiring antibiotic treatment and were monitored for 2 weeks showing a decrease of the pain, VAS, and PD signals. Five lesions showed subclinical calcinosis. This is the first study to show the promising role of US in defining skin ulcers of SSc patients. US may support the assessment of morphology and extent of skin ulcers in SSc and can be a helpful tool for detecting underlying pathology.
Wortsman, Ximena; Wortsman, J.; Orlandi, C.; Cárdenas, G.; Sazunic Yáñez, Ivo; Jemec, G. B. E(WILEY-BLACKWELL, 2012-03)
Background While the incidence of cosmetic filler injections is rising world-wide, neither exact details of the procedure nor the agent used are always reported or remembered by the patients. Thus, although complications ...