Dissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride
| Author | dc.contributor.author | Velasco-De-Paola, M. V.R. | |
| Author | dc.contributor.author | Santoro, M. I.R.M. | |
| Author | dc.contributor.author | Gai, M. N. | |
| Admission date | dc.date.accessioned | 2018-12-20T15:04:07Z | |
| Available date | dc.date.available | 2018-12-20T15:04:07Z | |
| Publication date | dc.date.issued | 1999 | |
| Cita de ítem | dc.identifier.citation | Drug Development and Industrial Pharmacy, Volumen 25, Issue 4, 2018, Pages 535-541 | |
| Identifier | dc.identifier.issn | 03639045 | |
| Identifier | dc.identifier.other | 10.1081/DDC-100102205 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/157453 | |
| Abstract | dc.description.abstract | In the present research, controlled-release propranolol hydrochloride tablets were prepared for twice-daily administration, allowing more uniform plasmatic levels of the drug. Pharmaceutical formulations were prepared with hydrophobic Eudragit® RSPO. The physical properties of the tablets were determined. Dissolution tests were performed in capsules containing the raw material using the following dissolution media: (A) distilled water, (B) simulated gastric juice without enzymes, and (C) simulated enteric juice without enzymes. A dissolution test was also performed for simulated samples (tablets) using distilled water as the dissolution medium. | |
| Lenguage | dc.language.iso | en | |
| Publisher | dc.publisher | Marcel Dekker Inc. | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Drug Development and Industrial Pharmacy | |
| Keywords | dc.subject | Medicine (all) | |
| Keywords | dc.subject | Pharmacology | |
| Keywords | dc.subject | Drug Discovery | |
| Keywords | dc.subject | Organic Chemistry | |
| Título | dc.title | Dissolution kinetics evaluation of controlled-release tablets containing propranolol hydrochloride | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile