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Authordc.contributor.authorSquella Serrano, Juan
Authordc.contributor.authorZanocco, A. 
Authordc.contributor.authorPerna, S. 
Authordc.contributor.authorNúñez Vergara, Luis 
Admission datedc.date.accessioned2018-12-20T15:05:12Z
Available datedc.date.available2018-12-20T15:05:12Z
Publication datedc.date.issued1990
Cita de ítemdc.identifier.citationJournal of Pharmaceutical and Biomedical Analysis, Volumen 8, Issue 1, 2018, Pages 43-47
Identifierdc.identifier.issn07317085
Identifierdc.identifier.other10.1016/0731-7085(90)80005-A
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/157721
Abstractdc.description.abstractNitrendipine produces a well-defined polarographic peak due to the four-electron reduction of the nitro group. This peak is used for tracking the photodecomposition of nitrendipine in both UV light and daylight conditions. The results show that nitrendipine remains unaltered in the short time scale of a normal analytical procedure and no special care with visible light exposure is necessary. However nitrendipine is strongly altered with UV irradiation showing a first-order degradation kinetics. A degradation rate constant of 0.0665 min-1 with a t 1 2, of 10.423 min has been obtained. The UV degradation product was isolated and identified as the nitro pyridine analogue of nitrendipine. © 1990.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceJournal of Pharmaceutical and Biomedical Analysis
Keywordsdc.subjectDifferential pulse polarography
Keywordsdc.subjectnitrendipine photodegradation.
Títulodc.titleA polarographic study of the photodegradation of nitrendipine
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile