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Authordc.contributor.authorValenzuela, M. A. 
Authordc.contributor.authorCollados, L. 
Authordc.contributor.authorKettlun, A. M. 
Authordc.contributor.authorMancilla, M. 
Authordc.contributor.authorPuente, J. 
Authordc.contributor.authorAranda, E. 
Authordc.contributor.authorChayet, L. 
Authordc.contributor.authorAlvarez, A. 
Authordc.contributor.authorTraverso Cori, A. 
Cita de ítemdc.identifier.citationComparative Biochemistry and Physiology -- Part B: Biochemistry and, Volumen 103, Issue 1, 2018, Pages 113-118
Abstractdc.description.abstract1. 1. The purpose of this present research was to explore the possible roles of ATP-diphosphohydrolase (apyrase) in two tissues with high energetic demands during cell proliferation and differentiation. 2. 2. Changes in apyrase activities during the pregnancy lactation cycle were examined in the rat uterus and mammary gland. 3. 3. A significant decrease in apyrase activity (ATPase-ADPase) was observed in the pregnant uterus; this observation correlates with a minor inhibitory effect on platelet aggregation. 4. 4. In mammary gland, the enzyme activity increases during lactation in parallel with an increase in blood supply, synthesis of glycoproteins and cell proliferation. 5. 5. Apyrase activity did not change during the estrous cycle. Estradiol administration to rats slightly increased (20%) both ATPase-ADPase activities. 6. 6. The probable function of apyrase in finally discussed, based on its substrate specifity and subcellular localization. © 1992.
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceComparative Biochemistry and Physiology -- Part B: Biochemistry and
Keywordsdc.subjectMolecular Biology
Títulodc.titleChanges in apyrase activity in uterus and mammary gland during the lactogenic cycle
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile