| Author | dc.contributor.author | Diaz, Eloisa | |
| Author | dc.contributor.author | Pesce, A. | |
| Admission date | dc.date.accessioned | 2018-12-20T15:09:22Z | |
| Available date | dc.date.available | 2018-12-20T15:09:22Z | |
| Publication date | dc.date.issued | 2000 | |
| Cita de ítem | dc.identifier.citation | Applied Organometallic Chemistry, Volumen 14, Issue 10, 2000, Pages 557-560 | |
| Identifier | dc.identifier.issn | 02682605 | |
| Identifier | dc.identifier.other | 10.1002/1099-0739(200010)14:10<557::AID-AOC38>3.0.CO;2-F | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/158045 | |
| Abstract | dc.description.abstract | The reaction of CpFe(dppe)I (Cp, cyclopentadienyl; dppe, Ph2P(CH2)(2)PPh2) with biologically active RSH molecules (L-cysteine hydrochloride, dithiothereitol and 2-mercaptoethanol) in the presence of NH4PF6 and in methanol as solvent afforded the new iron(III) thiolate complexes [CpFe(dppe)SR]PF6. The blue-black paramagnetic complexes were characterized by elemental analysis and IR, EPR and UV-visible spectroscopy. The selective S-H bond cleavage in the thiols suggests a possible utilization of the organometallic iron(II) complexes as inhibitors in some cysteine proteases, The spectroscopic properties of the new complexes have been compared with those of other Fe-S models as well as with Fe-S proteins. | |
| Lenguage | dc.language.iso | en | |
| Source | dc.source | Applied Organometallic Chemistry | |
| Keywords | dc.subject | Bond cleavage | |
| Keywords | dc.subject | Iron(III) complexes | |
| Keywords | dc.subject | Thiols | |
| Título | dc.title | S-H bond cleavage in molecules of biological interest with CpFe(dppe)I | |
| Document type | dc.type | Artículo de revista | |
| dcterms.accessRights | dcterms.accessRights | Acceso a solo metadatos | |
| Cataloguer | uchile.catalogador | rvh | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI | |
