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Author | dc.contributor.author | Criollo Céspedes, Alfredo | |
Author | dc.contributor.author | Senovilla, Laura | |
Author | dc.contributor.author | Authier, Hélène | |
Author | dc.contributor.author | Maiuri, Maria Chiara | |
Author | dc.contributor.author | Morselli, Eugenia | |
Author | dc.contributor.author | Vitale, Ilio | |
Author | dc.contributor.author | Kepp, Oliver | |
Author | dc.contributor.author | Tasdemir, Ezgi | |
Author | dc.contributor.author | Galluzzi, Lorenzo | |
Author | dc.contributor.author | Shen, Si | |
Author | dc.contributor.author | Tailler, Maximilien | |
Author | dc.contributor.author | Delahaye, Nicolas | |
Author | dc.contributor.author | Tesniere, Antoine | |
Author | dc.contributor.author | De Stefano, Daniela | |
Author | dc.contributor.author | Younes, Aména Ben | |
Author | dc.contributor.author | Harp | |
Admission date | dc.date.accessioned | 2018-12-20T15:10:24Z | |
Available date | dc.date.available | 2018-12-20T15:10:24Z | |
Publication date | dc.date.issued | 2010 | |
Cita de ítem | dc.identifier.citation | Autophagy, Volumen 6, Issue 1, 2018, Pages 189-191 | |
Identifier | dc.identifier.issn | 15548635 | |
Identifier | dc.identifier.issn | 15548627 | |
Identifier | dc.identifier.other | 10.4161/auto.6.1.10818 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/158163 | |
Abstract | dc.description.abstract | Cells respond to stress by activating cytoplasmic mechanisms as well as transcriptional programs that can lead to adaptation or death. Autophagy represents an important cytoprotective response that is regulated by both transcriptional and transcription-independent pathways. NFκB is perhaps the transcription factor most frequently activated by stress and has been ascribed with either pro- or anti-autophagic functions, depending on the cellular context. Our results demonstrate that activation of the IKK (IκB kinase) complex, which is critical for the stress-elicited activation of NFκB, is sufficient to promote autophagy independent of NFκB, and that IKK is required for the optimal induction of autophagy by both physiological and pharmacological autophagic triggers. © 2010 Landes Bioscience. | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | Taylor and Francis Inc. | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Autophagy | |
Keywords | dc.subject | AMPK | |
Keywords | dc.subject | JNK1 | |
Keywords | dc.subject | mTOR | |
Keywords | dc.subject | Nutrient deprivation | |
Keywords | dc.subject | Rapamycin | |
Título | dc.title | IKK connects autophagy to major stress pathways | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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