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Author | dc.contributor.author | Hosta-Rigau, Leticia | |
Author | dc.contributor.author | Olmedo, Ivonne | |
Author | dc.contributor.author | Arbiol, Jordi | |
Author | dc.contributor.author | Cruz, Luis J. | |
Author | dc.contributor.author | Kogan Bocian, Marcelo | |
Author | dc.contributor.author | Albericio, Fernando | |
Admission date | dc.date.accessioned | 2018-12-20T15:10:26Z | |
Available date | dc.date.available | 2018-12-20T15:10:26Z | |
Publication date | dc.date.issued | 2010 | |
Cita de ítem | dc.identifier.citation | Bioconjugate Chemistry, Volumen 21, Issue 6, 2018, Pages 1070-1078 | |
Identifier | dc.identifier.issn | 10431802 | |
Identifier | dc.identifier.issn | 15204812 | |
Identifier | dc.identifier.other | 10.1021/bc1000164 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/158176 | |
Abstract | dc.description.abstract | Functionalization of gold nanoparticles (AuNPs) with both a targeting peptide (an analogue of the peptide Bombesin) and a drug peptide ligand (an analogue of the RAF peptide) with the aim of improving selectivity in the delivery of the conjugates as well as the antitumor activity is described. Studies on the internalization mechanism of peptide-AuNP conjugates and viability of cells were carried out. An enhancement of the activity and selectivity of the peptide multifunctionalized conjugates was observed. © 2010 American Chemical Society. | |
Lenguage | dc.language.iso | en | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Bioconjugate Chemistry | |
Keywords | dc.subject | Biotechnology | |
Keywords | dc.subject | Bioengineering | |
Keywords | dc.subject | Biomedical Engineering | |
Keywords | dc.subject | Pharmacology | |
Keywords | dc.subject | Pharmaceutical Science | |
Keywords | dc.subject | Organic Chemistry | |
Título | dc.title | Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a tumor cell line | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile