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Author | dc.contributor.author | Aldabaldetrecu, Maialen | |
Author | dc.contributor.author | Tamayo, Laura | |
Author | dc.contributor.author | Alarcón, Romina | |
Author | dc.contributor.author | Walter, Mariana | |
Author | dc.contributor.author | Salas Huenuleo, Edison | |
Author | dc.contributor.author | Kogan Bocian, Marcelo | |
Author | dc.contributor.author | Guerrero, Juan | |
Author | dc.contributor.author | Páez, Maritza | |
Author | dc.contributor.author | Azócar, Manuel I. | |
Admission date | dc.date.accessioned | 2018-12-20T15:11:40Z | |
Available date | dc.date.available | 2018-12-20T15:11:40Z | |
Publication date | dc.date.issued | 2018 | |
Cita de ítem | dc.identifier.citation | Molecules, Volumen 23, Issue 7, 2018, | |
Identifier | dc.identifier.issn | 14203049 | |
Identifier | dc.identifier.other | 10.3390/molecules23071629 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/158421 | |
Abstract | dc.description.abstract | © 2018 by the authors. The antibacterial effects against Staphylococcus epidermidis of five silver carboxylate complexes with anti-inflammatory ligands were studied in order to analyze and compare them in terms of stability (in solution and after exposure to UV light), and their antibacterial and morphological differences. Four effects of the Ag-complexes were evidenced by transmission electronic microscopy (TEM) and scanning electronic microscopy (SEM): DNA condensation, membrane disruption, shedding of cytoplasmic material and silver compound microcrystal penetration of bacteria. 5-Chlorosalicylic acid (5Cl) and sodium 4-aminosalicylate (4A) were the most effective ligands for synthesizing silver complexes with high levels of antibacterial activity. However, Ag-5Cl was the most stable against exposure UV light (365 nm). Cytotoxic effects were tested against two kinds of eukaryotic cells: murine fibroblast cells (T10 1/2) and human epithelial ovarian cancer cells (A2780). The main obj | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | MDPI AG | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Molecules | |
Keywords | dc.subject | Human ovarian cancer cell (A2780) | |
Keywords | dc.subject | Murine fibroblast | |
Keywords | dc.subject | Silver antibacterial | |
Keywords | dc.subject | Staphylococcus epidermidis | |
Título | dc.title | Stability of antibacterial silver carboxylate complexes against staphylococcus epidermidis and their cytotoxic effects | |
Document type | dc.type | Artículo de revista | |
dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile