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Authordc.contributor.authorSierpe, Rodrigo 
Authordc.contributor.authorLang, Erika 
Authordc.contributor.authorJara, Paul 
Authordc.contributor.authorGuerrero, Ariel 
Authordc.contributor.authorChornik, Boris 
Authordc.contributor.authorKogan Bocian, Marcelo 
Authordc.contributor.authorYutronic Sáez, Nicolás 
Cita de ítemdc.identifier.citationACS Applied Materials and Interfaces, Volumen 7, Issue 28, 2015, Pages 15177-15181
Abstractdc.description.abstractWe report the synthesis of a 1:1 beta-cydodextrin-phenylethylamine (beta CD-PhEA) inclusion complex (IC) and the adhesion of gold nanoparticles (AuNPs) onto micro crystals of this complex, which forms a ternary system. The formation of the IC was confirmed by powder X-ray diffraction and NMR analyses (H-1 and ROESY). The stability constant of the IC (760 M-1) was determined using the phase solubility method. The adhesion of AuNPs was obtained using the magnetron sputtering technique, and the presence of AuNPs was confirmed using UV-vis spectroscopy (surface plasmon resonance effect), which showed. an absorbance at 533 nm. The powder X-ray diffractograms of beta CD-PhEA were similar to those of the crystals decorated with AuNPs. A comparison of the one- and two-dimensional NMR spectra of the IC with and without AuNPs suggests partial displacement of the guest to the outside of the beta CD due to attraction toward AuNPs, a characteristic tropism effect. The size, morphology, and distribution of the AuNPs were analyzed using TEM and SEM. The average size of the AuNPs was 14 nm. Changes in the IR and Raman spectra were attributed to the formation of the complex and to the specific interactions of this group with the AuNPs. Laser irradiation assays show that the ternary system beta CD-PhEA-AuNPs in solution enables the release of the guest.
Publisherdc.publisherAmerican Chemical Society
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceACS Applied Materials and Interfaces
Keywordsdc.subjectGold nanoparticles
Keywordsdc.subjectInclusion complex
Keywordsdc.subjectMagnetron sputtering
Keywordsdc.subjectPhotothermal effect
Títulodc.titleGold nanoparticles interacting with β-cyclodextrin-phenylethylamine inclusion complex: a ternary system for photothermal drug release
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile