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Authordc.contributor.authorCastro, Pablo 
Authordc.contributor.authorPérez, Osvaldo 
Authordc.contributor.authorGreig, Douglas 
Authordc.contributor.authorDíaz Araya, Guillermo 
Authordc.contributor.authorMoraga, Francisco 
Authordc.contributor.authorChiong Lay, Mario 
Authordc.contributor.authorTroncoso, Rodrigo 
Authordc.contributor.authorPadilla, Ivonne 
Authordc.contributor.authorVukasovic, Jose L. 
Authordc.contributor.authorCorbalán, Ramón 
Authordc.contributor.authorLavandero González, Sergio 
Cita de ítemdc.identifier.citationRevista Espanola de Cardiologia, Volumen 57, Issue 11, 2018, Pages 1053-1058
Abstractdc.description.abstractIntroduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, left ventricular function, oxidative stress levels and neurohumoral status at baseline and after 6 months of treatment with carvedilol in patients with chronic HF. Patients and method. Thirty patients with chronic HF that was stable without beta blocker treatment were included. Functional class was II or III, and left ventricular ejection fraction (LVEF) was < 40%. Mahler score, distance walked in 6 min, peak oxygen consumption, LVEF, plasma catecholamine (norepinephrine) concentration and oxidative stress parameters were evaluated at baseline and after 6 months of treatment with carvedilol. Results. Mean age was 59 (2) years, and 23 patients were men. After 6 months of treatment there were clinical improvements as measured by the Mahler score (from 6.8 to 11.0 point
Publisherdc.publisherEdiciones Doyma, S.L.
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceRevista Espanola de Cardiologia
Keywordsdc.subjectBeta blockers
Keywordsdc.subjectHeart failure
Keywordsdc.subjectOxidative stress
Títulodc.titleEffects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxi
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile