Histological maturation of the neocortex in phenylketonuric rats
| Author | dc.contributor.author | Cordero, Maria Elena | |
| Author | dc.contributor.author | Trejo, Manuel | |
| Author | dc.contributor.author | Colombo, Marta | |
| Author | dc.contributor.author | Aranda, Verónica | |
| Admission date | dc.date.accessioned | 2019-01-29T14:20:41Z | |
| Available date | dc.date.available | 2019-01-29T14:20:41Z | |
| Publication date | dc.date.issued | 1983 | |
| Cita de ítem | dc.identifier.citation | Early Human Development, Volumen 8, Issue 2, 2018, Pages 157-173 | |
| Identifier | dc.identifier.issn | 03783782 | |
| Identifier | dc.identifier.other | 10.1016/0378-3782(83)90072-5 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/160476 | |
| Abstract | dc.description.abstract | The histological maturation of pyramidal cells from the deeper layer of the neocortex was studied in phenylketonuric rats. The main alterations consist of a decrease in the number and span of dendritic basilar processes of large pyramidal cells, and changes in the structural organization of the cerebral cortex. It is postulated that high levels of phenylalanine induced immediately after birth disturb profoundly the process of neuronal maturation in the neocortex of the rat brain, probably with long-term effects. © 1983. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Early Human Development | |
| Keywords | dc.subject | maturation | |
| Keywords | dc.subject | neocortex | |
| Keywords | dc.subject | neuron | |
| Keywords | dc.subject | phenylalanine | |
| Título | dc.title | Histological maturation of the neocortex in phenylketonuric rats | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile