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Authordc.contributor.authorMora, Sergio 
Authordc.contributor.authorDíaz Véliz, Gabriela 
Admission datedc.date.accessioned2019-01-29T14:20:43Z
Available datedc.date.available2019-01-29T14:20:43Z
Publication datedc.date.issued1983
Cita de ítemdc.identifier.citationPharmacology, Biochemistry and Behavior, Volumen 19, Issue 2, 2018, Pages 157-161
Identifierdc.identifier.issn00913057
Identifierdc.identifier.other10.1016/0091-3057(83)90033-3
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/160489
Abstractdc.description.abstractThe influence of luteinizing hormone releasing hormone (LHRH) on the behavioral effects induced by several doses of D-amphetamine (0.25, 0.5, 1.0 and 2.0 mg/kg IP) was studied. A dose response relation was previously established for the effects of LHRH (50, 100 and 200 μg/kg SC) on acquisition and retention of conditioned avoidance responses (CARs). The neuropeptide impaired acquisition and improved retention of CARs, without modifying spontaneous motor activity. Pretreatment with 100 μg/kg of LHRH antagonizes the enhancement in acquisition of CARs due to D-amphetamine 0.5, 1.0 and 2.0 mg/kg, the impairment in retention induced by amphetamine 1.0 and 2.0 mg/kg, and the hypermotility and the increased rearing behavior induced by amphetamine 1.0 and 2.0 mg/kg. These results suggest that brain catecholamines, particularly dopamine, could play a role in the behavioral effects of LHRH. Interactions between LHRH and central dopaminergic mechanisms are discussed. © 1983.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourcePharmacology, Biochemistry and Behavior
Keywordsdc.subjectAmphetamine
Keywordsdc.subjectAvoidance behavior
Keywordsdc.subjectDopamine
Keywordsdc.subjectLHRH
Keywordsdc.subjectMotor activity
Títulodc.titleInfluence of luteinizing hormone releasing hormone (LHRH) on the behavioral effects of amphetamine in rats
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile