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Authordc.contributor.authorValenzuela Bonomo, Carlos 
Authordc.contributor.authorBarría, Teresa 
Authordc.contributor.authorGuerra, Ricardo 
Authordc.contributor.authorGarrido, Argelia 
Admission datedc.date.accessioned2019-01-29T14:47:10Z
Available datedc.date.available2019-01-29T14:47:10Z
Publication datedc.date.issued1985
Cita de ítemdc.identifier.citationBiochemical and Biophysical Research Communications, Volumen 126, Issue 2, 2018, Pages 712-718
Identifierdc.identifier.issn10902104
Identifierdc.identifier.issn0006291X
Identifierdc.identifier.other10.1016/0006-291X(85)90243-8
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/160566
Abstractdc.description.abstractThe flavonoid silymarin, which is used as a therapeutical agent in the treatment of liver diseases, can inhibit the hemolysis and lipid peroxidation induced by phenylhydrazine on erythrocytes obtained from rats treated with the flavonoid. This effect is ascribed to the antioxidant properties as a free radical scavenger exhibited by the flavonoid. Silymarin failed to inhibit the glutathione depletion induced by phenylhydrazine on erythrocytes. It is proposed that the flavonoid acts at the membrane level of the cell avoiding the lipid peroxidative and fluidizing effect of phenylhydrazine. © 1985.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceBiochemical and Biophysical Research Communications
Keywordsdc.subjectBiochemistry
Keywordsdc.subjectBiophysics
Keywordsdc.subjectMolecular Biology
Títulodc.titleInhibitory effect of the flavonoid silymarin on the erythrocyte hemolysis induced by phenylhydrazine
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile