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Authordc.contributor.authorFernández Arancibia, Virginia 
Authordc.contributor.authorLlesuy, Susana 
Authordc.contributor.authorSolari, L. 
Authordc.contributor.authorKipreos, Katina 
Authordc.contributor.authorVidela Cabrera, Luis
Authordc.contributor.authorBoveris, A. 
Cita de ítemdc.identifier.citationFree Radical Research, Volumen 5, Issue 2, 2018, Pages 77-84
Abstractdc.description.abstractChemiluminescent and respiratory responses were studied in the liver of rats treated with 0.1 mg of triiodothyronine (T)/kg for I to 7 days. Hyperthyroidism resulted in significant increments in the spontaneous chemiluminescence of the in situ liver in animals exhibiting a calorigenic response. Microsomal NADPH-dependent oxygen uptake was enhanced by T, treatment for 2 days. an effect that was completely abolished by the antioxidant cyanidanol. A similar microsomal antioxidant-sensitive respiratory component was observed in this situation aftcr the addition of t-butyl hydroperoxide (t-BHP). However, basal rates of microsomal oxygen uptake and light emission in liver homogenates and microsomes were decreased by t-BHP, probably related to thyroid hormone-induced diminution in the content of cytochrome P-450 (Fernändez ei a/.) In addition, liver superoxide dismutase and catalase activities as well as the total content of glutathione were depressed by T, These results indicate that the cal
Publisherdc.publisherInforma Healthcare
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceFree Radical Research
Keywordsdc.subjectOxidative stress
Keywordsdc.subjectOxygen uptake
Keywordsdc.subjectThyroid hormone
Títulodc.titleChemiluminescent and respiratory responses related to thyroid hormone-induced liver oxidative stress
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile