Intraarticular progesterone: Effects of a local treatment for rheumatoid arthritis
Author
dc.contributor.author
Cuchacovich Turteltaub, Miguel
Author
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Tchernitchin,
Author
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Gatica,
Author
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Wurgaft,
Author
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Valenzuela,
Author
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Cornejo Cornejo, Jacqueline Alejandra
Admission date
dc.date.accessioned
2019-01-29T14:48:01Z
Available date
dc.date.available
2019-01-29T14:48:01Z
Publication date
dc.date.issued
1988
Cita de ítem
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Journal of Rheumatology, Volumen 15, Issue 4, 2018, Pages 561-565
Identifier
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0315162X
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/160699
Abstract
dc.description.abstract
The antiinflammatory effect of a single intraarticular injection of progesterone was investigated in 12 patients with rheumatoid arthritis. A local, but no systemic decline of inflammation was observed in 10 of them for at least one month. The average local scores of inflammation at Days 7, 14, 21 and 30 after injection were significantly lower than pretreatment scores (p < 0.000003 for each comparison). In some patients, the effect continued for up to 2 months. No important side effects were observed during the following 2 months. However, a more prolonged followup of treated patients is necessary to rule out the late onset of side effects.