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Authordc.contributor.authorPerretta, Marco 
Authordc.contributor.authorGarrido, Fernando 
Authordc.contributor.authorEscárate, Patricia 
Admission datedc.date.accessioned2019-01-29T14:48:31Z
Available datedc.date.available2019-01-29T14:48:31Z
Publication datedc.date.issued1988
Cita de ítemdc.identifier.citationNutrition Research, Volumen 8, Issue 12, 2018, Pages 1421-1429
Identifierdc.identifier.issn02715317
Identifierdc.identifier.other10.1016/S0271-5317(88)80010-1
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/160709
Abstractdc.description.abstractRNA synthesis was studied in bone marrow of rats with protein-energy malnutrition (PEM) and protein malnutrition (PM) after the administration of erythro-poietin (Epo) and/or testosterone (Te). RNA synthesis appeared slighty increased in PEM animals, 25% by Epo; 66% by Te while not alteration was induced by Epo and Te together. In PM rats a considerable decrease of RNA synthesis was observed. These results would indicate that the use of 14C-formate as a labelled precursor to estimate DE NOVO RNA synthesis is a reliable experimental variable for testing bone marrow function. The data presented suggest that while in PEM the biochemical machinery required to synthesize RNA remains basically unchanged. PM induces important metabolic disturbance. © 1988 Pergamon Press plc. All rights reserved.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceNutrition Research
Keywordsdc.subjectErythropoiesis
Keywordsdc.subjecterythropoietin
Keywordsdc.subjectprotein-energy malnutrition and protein malnutrition
Keywordsdc.subjectRNA
Keywordsdc.subjecttestosterone
Títulodc.titleEffect of erythropoietin and testosterone on bone marrow RNA synthesis in rats with protein-energy or protein malnutrition
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile