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Author | dc.contributor.author | Hidalgo Tapia, María Cecilia | |
Author | dc.contributor.author | Jaimovich Pérez, Enrique | |
Admission date | dc.date.accessioned | 2019-01-29T14:48:34Z | |
Available date | dc.date.available | 2019-01-29T14:48:34Z | |
Publication date | dc.date.issued | 1989 | |
Cita de ítem | dc.identifier.citation | Journal of Bioenergetics and Biomembranes, Volumen 21, Issue 2, 2018, Pages 267-281 | |
Identifier | dc.identifier.issn | 0145479X | |
Identifier | dc.identifier.issn | 15736881 | |
Identifier | dc.identifier.other | 10.1007/BF00812072 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/160723 | |
Abstract | dc.description.abstract | The role of inositol trisphosphate as a chemical messenger in excitation-contraction coupling is discussed, both in terms of positive and negative results. The evidence presented includes experiments on the effect of inositol trisphosphate in intact and skinned fibers, in calcium release from isolated sarcoplasmic reticulum vesicles, in activation of single calcium release channels incorporated in planar bilayers, and biochemical experiments that have established the presence of all the intermediate steps involved in the metabolism of phosphoinositides, both in intact muscle and in isolated membranes. From these results, it is clear that a role for inositol triphosphate in skeletal muscle function is highly likely; whether this molecule is the physiological messenger in excitation-contraction coupling remains to be established. © 1989 Plenum Publishing Corporation. | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | Kluwer Academic Publishers-Plenum Publishers | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Journal of Bioenergetics and Biomembranes | |
Keywords | dc.subject | Calcium channels | |
Keywords | dc.subject | excitation-contraction coupling | |
Keywords | dc.subject | inositol trisphosphate | |
Keywords | dc.subject | phosphoinositide metabolism | |
Keywords | dc.subject | sarcoplasmic reticulum | |
Keywords | dc.subject | skeletal muscle | |
Keywords | dc.subject | skinned fibers | |
Keywords | dc.subject | transverse tubules | |
Título | dc.title | Inositol trisphosphate and excitation-contraction coupling in skeletal muscle | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile