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Authordc.contributor.authorValenzuela, 
Admission datedc.date.accessioned2019-01-29T14:49:26Z
Available datedc.date.available2019-01-29T14:49:26Z
Publication datedc.date.issued1990
Cita de ítemdc.identifier.citationRevista medica de Chile, Volumen 118, Issue 9, 2018, Pages 1028-1034
Identifierdc.identifier.issn00349887
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/160860
Abstractdc.description.abstractMetabolic changes sustained by foreign substances (biotransformation), xenobiotics, may not always lead to a decreased toxicity from these substances. Metabolic activation, a process that may increase toxicity and chemical reactivity of these substances, may occur at the first or second phase of biotransformation. Electrophiles of nucleophiles may be formed. Lipoperoxidation by free oxygen radicals may thus follow. Details of these processes are discussed in the paper.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceRevista medica de Chile
Keywordsdc.subjectMedicine (all)
Títulodc.titleMetabolic activation: a biological mechanism that augments the toxicity of xenobiotics Activación metabólica: un mecanismo biológico que aumenta la toxicidad de los xenobióticos.
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile