The IgG antibody response in patients colonized by Helicobacter pylori Respuesta de anticuerpos IgG en pacientes colonizados por Helicobacter pylori.
Author
dc.contributor.author
Figueroa Figueroa, Mónica
Author
dc.contributor.author
Acuña Acuña, Jeannette
Author
dc.contributor.author
Jashés,
Author
dc.contributor.author
Troncoso, Sofía
Author
dc.contributor.author
Toledo Toledo, Gladys Luisa
Author
dc.contributor.author
Arellano,
Admission date
dc.date.accessioned
2019-01-29T14:49:28Z
Available date
dc.date.available
2019-01-29T14:49:28Z
Publication date
dc.date.issued
1990
Cita de ítem
dc.identifier.citation
Revista medica de Chile, Volumen 118, Issue 11, 2018, Pages 1195-1200
Identifier
dc.identifier.issn
00349887
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/160872
Abstract
dc.description.abstract
The IgG antibody response specific to Helicobacter pylori was evaluated through ELISA in a group of 92 gastric patients colonized by this bacteria. 74 had gastritis and 19 gastroduodenal ulcer. Three control groups were studied in a similar way: normal adult volunteers (n = 17), adults with E coli or S typhi bacteremia (n = 30) and normal infants (n = 30). IgG antibody response to H pylori was demonstrated in 98% of colonized patients and 0% of infants. Asymptomatic individuals and those with bacteremia had high rates of antibody response (76 and 90% respectively), although this rate and also the titers of antibody response were significantly lower than that of colonized patients (p < 0.05). ELISA reactive sera from colonized patients and asymptomatic individuals evidenced a similar antibody pattern when tested by blotting. This profile was absent in non reactive sera, including those with high antibody titers to C jejuni. The presence of specific IgG antibodies to H pylori in the majo