Environmental deprivation delays the maturation of motor pyramids during the early postnatal period
Author
dc.contributor.author
Pascual, Rodrigo
Author
dc.contributor.author
Fernández, Victor
Author
dc.contributor.author
Ruiz, Samuel
Author
dc.contributor.author
Kuljis, Rodrigo O.
Admission date
dc.date.accessioned
2019-01-29T14:51:19Z
Available date
dc.date.available
2019-01-29T14:51:19Z
Publication date
dc.date.issued
1993
Cita de ítem
dc.identifier.citation
Early Human Development, Volumen 33, Issue 2, 2018, Pages 145-155
Identifier
dc.identifier.issn
03783782
Identifier
dc.identifier.other
10.1016/0378-3782(93)90209-D
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/160991
Abstract
dc.description.abstract
The effects of environmental deterioration upon the development of motor cortex was studied in 30 Sprague-Dawley albino rats during lactation (1st-18th postnatal days). The use of Golgi-Cox-Sholl methodology allowed qualitative and particularly quantitative evaluations since impregnation of neurons take place at random without any selectivity. Morphometric studies were assessed by measuring layers II-III pyramidal neurons, basal dendritic branching, under camera lucida. Early environmental impoverishment results in a highly significant decrease in the number and length of peripherical branches and terminal dendrites. These results extend previous observations made predominantly in non-motor cortices which indicate that during early postnatal life restrictions or enrichments of the environment may be associated with quantitative changes in the differentiation of cerebrocortical neurons. It is of upmost importance to consider that the potential effects of different types of epigenetic cu