Relationship between DNA methylation and cell proliferation in Trypanosoma cruzi
| Author | dc.contributor.author | Rojas, M.Verónica | |
| Author | dc.contributor.author | Galanti Garrone, Norbel | |
| Admission date | dc.date.accessioned | 2019-01-29T14:52:14Z | |
| Available date | dc.date.available | 2019-01-29T14:52:14Z | |
| Publication date | dc.date.issued | 1991 | |
| Cita de ítem | dc.identifier.citation | FEBS Letters, Volumen 295, Issue 1-3, 2018, Pages 31-34 | |
| Identifier | dc.identifier.issn | 00145793 | |
| Identifier | dc.identifier.other | 10.1016/0014-5793(91)81377-K | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/161053 | |
| Abstract | dc.description.abstract | 5-Azacytidine treatment of T. cruzi epimastigotes in culture induces active cell proliferation. This effect was detected as an increase in the cell number and [3H-methyl]thymidine incorporation into DNA. 5-Azacytidine does not alter other metabolic parameters. We have previously demonstrated that 5-azacytidine induces DNA hypomethylation in T. cruzi. Accordingly, we suggest that this chemical modification may be related to the control of T. cruzi cell division. © 1991. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | FEBS Letters | |
| Keywords | dc.subject | 5-Azacytidine | |
| Keywords | dc.subject | Cell proliferation | |
| Keywords | dc.subject | DNA methylation | |
| Keywords | dc.subject | Trypanosoma cruzi | |
| Título | dc.title | Relationship between DNA methylation and cell proliferation in Trypanosoma cruzi | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile