Evaluation of commercially available reagents for diagnosis of chagas disease in Chilean blood banks. I. Selection of reagents Evaluacion de reactivos comerciales empleados en el diagnostico de la enfermedad de Chagas en bancos de Sangre de Chile. I selec
Author
dc.contributor.author
Lorca,
Author
dc.contributor.author
Child,
Author
dc.contributor.author
García García, Patricio Andrés
Author
dc.contributor.author
Silva Silva, Laura
Author
dc.contributor.author
Osorio Osorio, Francisco Antonio
Author
dc.contributor.author
Atías,
Admission date
dc.date.accessioned
2019-01-29T14:52:23Z
Available date
dc.date.available
2019-01-29T14:52:23Z
Publication date
dc.date.issued
1992
Cita de ítem
dc.identifier.citation
Revista medica de Chile, Volumen 120, Issue 4, 2018, Pages 420-426
Identifier
dc.identifier.issn
00349887
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/161112
Abstract
dc.description.abstract
Infection with T cruzi through blood transfusion is an important public health problem in Latin America, including Chile. A study on the sensitivity, specificity and applicability of currently applied methods was performed. Ten commercially available products were tested in a panel of 180 blood specimens against the indirect immunofluorescence antibody test (IFAT) and the immunoperoxidase test (IP). Qualitative concordance ranged from 82 to 98%, sensitivity from 64 to 97% and specificity from 93 to 100%. Some commercial products had a low performance and ELISA is recommended for routine use in Chilean blood banks, given its significantly higher sensitivity and specificity when compared to the hemagglutination test. In addition, experience with the use of the ELISA test is widespread in Chile.
Evaluation of commercially available reagents for diagnosis of chagas disease in Chilean blood banks. I. Selection of reagents Evaluacion de reactivos comerciales empleados en el diagnostico de la enfermedad de Chagas en bancos de Sangre de Chile. I selec