Primary hyperparathyroidism caused by a mediastinal adenoma with intermittent hypercalcemia and severe bone disease Hiperparatiroidismo primario por adenoma mediastínico, con hipercalcemia intermitente y enfermedad ósea acentuada.
Author
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Araya Araya, Fernando
Author
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Pumarino, Diego
Author
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Larenas, J.
Author
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Gac,
Admission date
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2019-01-29T14:52:23Z
Available date
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2019-01-29T14:52:23Z
Publication date
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1992
Cita de ítem
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Revista medica de Chile, Volumen 120, Issue 5, 2018, Pages 563-570
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/161115
Abstract
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We report the case of a 33-year-old woman who was operated on with the diagnosis of primary hyperparathyroidism (PHP) in 1986. She had bone disease and slight hypercalcemia. Two parathyroid glands were removed with a lack of clinical improvement. Subsequently, the serum calcium levels were normal with occasional slight increases. Depressed phosphorus values and elevated alkaline phosphatases and PTH levels were also present, associated with severe bone involvement and muscular weakness. A second cervical exploration performed in 1989 disclosed only a normal parathyroid gland, which was not removed. In 1990, a thoracic CT scan showed the presence of a 1 cm mediastinal nodule close to the great vessels. A thoracotomy was performed to remove this nodule, which proved to be a parathyroid adenoma. After surgery, the patient presented with a "hungry bone" syndrome, characterized by very low levels of calcium, phosphorus and magnesium, which required enteral and parenteral calcium and magnesi
Primary hyperparathyroidism caused by a mediastinal adenoma with intermittent hypercalcemia and severe bone disease Hiperparatiroidismo primario por adenoma mediastínico, con hipercalcemia intermitente y enfermedad ósea acentuada.