Bone marrow ribonucleic acid polymerase. Effect of testosterone on nucleotide incorporation into nuclear RNA
Author
dc.contributor.author
Valladares Boasi, Luis
Author
dc.contributor.author
Cañas, Patricio E.
Author
dc.contributor.author
Minguell, José J.
Admission date
dc.date.accessioned
2019-01-29T15:34:42Z
Available date
dc.date.available
2019-01-29T15:34:42Z
Publication date
dc.date.issued
1976
Cita de ítem
dc.identifier.citation
Nucleic Acids Research, Volume 3 no.11 November 1976
Identifier
dc.identifier.issn
03051048
Identifier
dc.identifier.other
10.1093/nar/3.11.3077
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/161702
Abstract
dc.description.abstract
The incorporation of 3H UTP into RNA by isolated rat bone marrow nuclei is stimulated by testosterone. This effect is hormone and tissue specific. Using α amanitine and different ionic strength conditions it was found that testosterone enhances preferentially RNA polymerase I activity. The sedimentation pattern of RNA isolated from bone marrow nuclei shows that the synthesis of RNA species within the 14 to 30 S range is mainly stimulated by the hormone.