Multiple conductance states of the light-activated channel of Limulus ventral photoreceptors: Alteration of Conductance State during Light
Author
dc.contributor.author
Johnson, Edwin C.
Author
dc.contributor.author
Bacigalupo Vicuña, Juan
Author
dc.contributor.author
Vergara Montecinos, Cecilia
Author
dc.contributor.author
Lisman, John E.
Admission date
dc.date.accessioned
2019-01-29T15:47:28Z
Available date
dc.date.available
2019-01-29T15:47:28Z
Publication date
dc.date.issued
1991
Cita de ítem
dc.identifier.citation
Journal of General Physiology, Volumen 97, Issue 6, 2018, Pages 1187-1205
Identifier
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15407748
Identifier
dc.identifier.issn
00221295
Identifier
dc.identifier.other
10.1085/jgp.97.6.1187
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/162374
Abstract
dc.description.abstract
The properties of light-dependent channels in Limulus ventral photoreceptors have been studied in cell-attached patches. Two sizes of single-channel events are seen during illumination. Previous work has characterized the large (40 pS) events; the goal of the current work was to characterize the small (15 pS) events and determine their relationship to the large events. The small events are activated by light rather than as a secondary result of the change in membrane voltage during light. The mean open time of the small events is 1.34 ± 0.49 ms (mean ± SD, n = 15), ~50% of that of the large events. The large and small events have the same reversal potential and a similar dependence of open-state probability on voltage. Evidence that these events are due to different conductance states of the same channel comes from analysis of relatively infrequent events showing a direct transition between the 15 and 40-pS levels. Furthermore, large and small events do not superpose, even at positive