Autoimmune phenomena in the elderly Fenómenos autoinmunes en la tercera edad.
Author
dc.contributor.author
Pérez,
Author
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Rodríguez Rodríguez, Pablo Andrés
Author
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Sepúlveda Sepúlveda, Ximena Andrea
Author
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Silva Silva, Laura
Admission date
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2019-01-29T15:47:34Z
Available date
dc.date.available
2019-01-29T15:47:34Z
Publication date
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1991
Cita de ítem
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Revista medica de Chile, Volumen 119, Issue 3, 2018, Pages 287-292
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/162409
Abstract
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We analyzed sera from 102 subjects older than 65 years of age with no clinical evidence of autoimmune disorders, inflammatory diseases or pharmacological interventions. Positive titers for antinuclear antibodies were found in 18.6%, anti-smooth muscle fibre in 16.6%, and rheumatoid factor in 11.8%. These values were significantly higher than those of a control group of healthy younger adults (p < 0.0001). Anti mitochondrial antibodies were present in 1% (NS). Thus, a greater proportion of autoimmune phenomena is demonstrated in the elderly.