Comparison of extra renal potassium disposal in hypertensive, diabetic and normal subjects Estudio comparativo del manejo extrarrenal de potasio en sujetos controles, pacientes hipertensos y diabéticos
Author
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Michea Acevedo, Luis
Author
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Alvo Abodovsky, Miriam
Author
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Morales, Helia
Author
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Brito, Julio
Author
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Peters, Gabriela
Author
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Marusic, Elisa
Admission date
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2019-01-29T15:55:12Z
Available date
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2019-01-29T15:55:12Z
Publication date
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1997
Cita de ítem
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Revista Medica de Chile, Volumen 125, Issue 11, 2018, Pages 1292-1298
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/162813
Abstract
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Background: Sodium and potassium ions are involved in the regulation of blood pressure and the genesis of hypertension. Aim: To assess internal potassium balance, as a measure of sodium pump activity, in subjects with essential hypertension and diabetic patients. Patients and methods: Eleven hypertensive subjects, 5 non-insulin-dependent diabetics and 16 age matched controls were studied. An acute oral load of 0.8 mEq/Kg body weight of KCl was administered and blood samples were drawn every 30 min thereafter, until 120 min, to measure plasma K+ levels. Urinary K+ excretion during this period was also measured. In eight hypertensive patients, the test was repeated after two week of supplementation with 60 mEq/day of KCl. The maximal increase in plasma potassium levels and the time required to achieve the maximum concentration was recorded. Results: All patients had normal serum creatinine levels. Mean fasting blood glucose of diabetic patients was 133 ± 15.1 mg/dl. No difference between
Comparison of extra renal potassium disposal in hypertensive, diabetic and normal subjects Estudio comparativo del manejo extrarrenal de potasio en sujetos controles, pacientes hipertensos y diabéticos