Severe community-acquired pneumonia: Assessment of severity criteria
Author
dc.contributor.author
Ewig, Santiago
Author
dc.contributor.author
Ruiz, Mauricio
Author
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Mensa, Josep
Author
dc.contributor.author
Marcos, Maria Angeles
Author
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Martinez, Jose Antonio
Author
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Arancibia, Francisco
Author
dc.contributor.author
Niederman, Michael S.
Author
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Torres, Antoni
Admission date
dc.date.accessioned
2019-01-29T17:15:54Z
Available date
dc.date.available
2019-01-29T17:15:54Z
Publication date
dc.date.issued
1998
Cita de ítem
dc.identifier.citation
American Journal of Respiratory and Critical Care Medicine, Volumen 158, Issue 4, 2018, Pages 1102-1108
Identifier
dc.identifier.issn
1073449X
Identifier
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10.1164/ajrccm.158.4.9803114
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/163349
Abstract
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The purpose of the study was to validate the criteria used in the guidelines of the American Thoracic Society (ATS) for severe community- acquired pneumonia (CAP). Severe pneumonia was defined as admission to the intensive care unit (ICU). Overall 331 nonsevere (84%) and 64 severe cases (16%) of CAP were prospectively studied. Mortality was 19 of 395 (5%) and 19 of 64 (30%), respectively. Single severity criteria as well as the ATS definition of severe pneumonia were assessed calculating the operative indices. A modified prediction rule including minor (baseline) and major (baseline or evolutionary) criteria was derived. Single minor criteria at admission had a low sensitivity and positive predictive value. Defining severe pneumonia according to the ATS guidelines had a high sensitivity (98%). However, specificity and positive predictive value were low (32% and 24%, respectively). A modified prediction rule (presence of two or three minor criteria [systolic blood pressure < 90 mm Hg, m