High prevalence of down syndrome in the Rancagua Hospital in central Chile Alta prevalencia de síndrome de down en el Hospital Regional Rancagua, Chile. Período 1997-2003
Author
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Ojeda B, María Elena
Author
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Moreno S, Rodrigo
Admission date
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2019-01-29T17:56:57Z
Available date
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2019-01-29T17:56:57Z
Publication date
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2005
Cita de ítem
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Revista Medica de Chile, Volumen 133, Issue 8, 2018, Pages 935-942
Identifier
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00349887
Identifier
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07176163
Identifier
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https://repositorio.uchile.cl/handle/2250/163898
Abstract
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Background: The Latin American Collaborative Study for Congenital Malformations (ECLAMC) has detected a higher incidence of Down syndrome in a zone of central Chile than in the rest of the country. Aim: To analyze the incidence rates of Down syndrome between 1997 and 2003 at the Regional Hospital of Rancagua, located 90 km south of Santiago, Chile. Material and methods: The information obtained by ECLAMC was used. This program, using a case control methodology, registers all newborns with congenital malformations and assigns, as a control, the next normal newborn of the same sex. Results: During the study period, 106 newborns with Down syndrome were registered, with a mean rate of 29.61 per 10,000 live births, twice higher than expected. The rate variations along the years of study suggest a cyclic change, with a hemicycle of six years. Conclusions: In this hospital, mothers under 35 years of age, have twice the risk of having a child with Down syndrome, than in the rest of the country
High prevalence of down syndrome in the Rancagua Hospital in central Chile Alta prevalencia de síndrome de down en el Hospital Regional Rancagua, Chile. Período 1997-2003