Ablation of stage T1/T2 prostate cancer with permanent interstitial temperature self-regulating rods
Author
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Tucker, Robert D.
Author
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Huidobro, Christian
Author
dc.contributor.author
Larson, Thayne
Admission date
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2019-01-29T17:56:59Z
Available date
dc.date.available
2019-01-29T17:56:59Z
Publication date
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2005
Cita de ítem
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Journal of Endourology, Volumen 19, Issue 7, 2018, Pages 865-867
Identifier
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08927790
Identifier
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10.1089/end.2005.19.865
Identifier
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https://repositorio.uchile.cl/handle/2250/163902
Abstract
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Purpose: To determine if stage T1/T2 prostate cancer can be treated safely and effectively with interstitial thermal ablation. Patients and Methods: Twenty patients with biopsy-confirmed prostate cancer were enrolled in the protocol. The average age was 71.0 years, and the pretreatment prostate specific antigen (PSA) concentration ranged from 2.5 to 10.7 ng/mL and the Gleason sum from 3 to 7. An array of small biocompatible magnetic alloy rods was placed in the patients percutaneously in a procedure analogous to the placement of brachytherapy seeds. Rods were placed end-to-end and no further than 1 cm apart; rods extended to the capsule and were placed at the capsule in the rectal grove. The rods are temperature self-regulating and heat to 70°C when placed in an alternating magnetic field. Each patient was treated in a coil system that supplies a uniform magnetic field throughout the patient's pelvis for a single 60-minute session. Urethral cooling and rectal temperature monitoring was