Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases Eficacia del infliximab en pacientes con síndrome de Behçet portadores de úveo-retinitis grave

Abstract

The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was suppressed in all patients during the observation period without any serious adverse reactions. The results in these patients suggests that TNF-α blockade is effective in patients with severe ocular Behçet syndrome.