Histological study on the male reproductive organs of mouse CF1 treated with boron
Author
dc.contributor.author
Espinoza Navarro, Omar
Author
dc.contributor.author
Vilaxa, A.
Author
dc.contributor.author
Granifo, L.
Author
dc.contributor.author
Rojas, S.
Author
dc.contributor.author
Rodríguez, H.
Admission date
dc.date.accessioned
2019-03-11T12:54:23Z
Available date
dc.date.available
2019-03-11T12:54:23Z
Publication date
dc.date.issued
2007
Cita de ítem
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International Journal of Morphology, Volumen 25, Issue 2, 2018, Pages 341-346
Identifier
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07179502
Identifier
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07179367
Identifier
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10.4067/S0717-95022007000200017
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/164403
Abstract
dc.description.abstract
Boric acid and borate are abundant in the nature and widely used in industrial, agricultural and cosmetology applications. However it is informed as toxic in a high dose. Residents of Arica-Chile with boron-rich geology deposits are regularly exposed to higher levels in drinking water in concentrations of 6. 0 and 12.0 mg/L. The objective of this study was to analyze the damage in the masculine reproductive apparatus of mouse CF1, exposed to boric acid in concentrations of 0.54; 2.0-6.0 and 12.0 mg/L, after 60 days of treatment. Male gonad segments were fixed in Bouin's solution for 6 hours and embedded in paraffin, longitudinal sections (5 mm) were processed for histology using the hematoxyline/eosin method. The results observed in treated animals indicate a significant increase in the weight, volume and size of testicles and seminal vesicles. The histological analysis of testicle shows in treated an epithelium notoriously altered with vacuohzations, scarce gonias and few spermatids.