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Authordc.contributor.authorGreig, Douglas 
Authordc.contributor.authorCastro, Pablo 
Authordc.contributor.authorGabrielli, Luigi 
Authordc.contributor.authorMiranda, Rodrigo 
Authordc.contributor.authorVerdejo, Hugo 
Authordc.contributor.authorAlcaíno Gálvez, Hernán Alejandro 
Authordc.contributor.authorBustos, Carlos 
Authordc.contributor.authorChiong Lay, Mario 
Authordc.contributor.authorGodoy, Iván 
Authordc.contributor.authorMellado, Rosemarie 
Authordc.contributor.authorGarcía Nannig, Lorena 
Authordc.contributor.authorSalas, Daniela 
Authordc.contributor.authorVivar, Raúl 
Authordc.contributor.authorVukasovic, José Luis 
Authordc.contributor.authorConcepción, Roberto 
Authordc.contributor.authorDíaz Araya, Guillermo 
Cita de ítemdc.identifier.citationRevista Medica de Chile, Volumen 136, Issue 6, 2018, Pages 687-693
Abstractdc.description.abstractBackground: In chronic heart failure (CHF), endothelial dysfunction (ED) is a consequence of an imbalance of vascular tone regulating substances. The relationship between ED and inflammation has not been fully investigated. Aim: To assess the association between inflammation and ED in CHF. Material and methods: Forty two patients aged 56±14 years (80% male) with a CHF in functional capacity II-III (New York Heart Association) and an ejection fraction (EF) <40% were consecutively studied. Patients were classified according to the presence or absence of ED, evaluated by reactive vasodilation measured by ultrasound, after brachial artery compression. Circulating levels of highly sensitive C reactive protein (usCRP), tumor necrosis factor α (TNFα) and interleukin-6 (IL-6) were determined by ELISA. A group of 15 healthy subjects of similar age, were studied as controls. Results: Sixty seven percent of patients had ED. Compared to controls, patients with CHF had higher usCRP (0.58±0.4 and 4.
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceRevista Medica de Chile
Keywordsdc.subjectEndothelium, vascular
Keywordsdc.subjectHeart failure
Títulodc.titleInflammation and endothelial dysfunction in patients with chronic heart failure Inflamación y disfunción endotelial en pacientes con insuficiencia cardiaca crónica
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile