Graft versus host disease with oral involvement. Report of one case Enfermedad injerto contra huésped (EICH). Caso clínico con expresión en mucosa bucal

Abstract

Graft versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent local complications which interfere with normal oral functions and facilitate infection spread. We report a 17 years old woman with GVHD associated to lichenoid and ulcerative lessions in the oral mucosa, which responded to the topical administration of a 0.1% tacrolimus ointment (Rev Méd Chile 2008; 136: 1570-3).