Iron absorption and iron status are reduced after Roux-en-Y gastric bypass
Author
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Ruz, Manuel
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Carrasco, Fernando
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Arenas Rojas, Pamela
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Codoceo, Juana
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Inostroza, Jorge
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Rebolledo, Annabella
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Basfi-fer Obregón, Karen
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Csendes Juhasz, Attila
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Papapietro Vallejo, Karin
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Pizarro Aguirre, Fernando
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Olivares, Manuel
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Sian, Lei
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Westcott, Jamie L.
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Hambidge, K. Michael
Author
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Krebs, Nancy F.
Admission date
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2019-03-11T12:58:13Z
Available date
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2019-03-11T12:58:13Z
Publication date
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2009
Cita de ítem
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American Journal of Clinical Nutrition, Volumen 90, Issue 3, 2018, Pages 527-532
Identifier
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00029165
Identifier
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10.3945/ajcn.2009.27699
Identifier
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https://repositorio.uchile.cl/handle/2250/164844
Abstract
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Background: Iron deficiency and iron deficiency anemia are common in patients who undergo gastric bypass. The magnitude of change in iron absorption is not well known. Objective: The objective was to evaluate the effects of Roux-en-Y gastric bypass (RYGBP) on iron status and iron absorption at different stages after surgery. We hypothesized that iron absorption would be markedly impaired immediately after surgery and would not improve after such a procedure. Design: Anthropometric, body-composition, dietary, hematologic, and iron-absorption measures were determined in 67 severe and morbidly obese women [mean age: 36.9 ± 9.8 y; weight: 115.1 ± 15.6 kg, body mass index (BMI: in kg/m2); 45.2 ± 4.7] who underwent RYGBP. The Roux-en-Y loop length was 125-150 cm. Determinations were carried out before and 6, 12, and 18 mo after surgery. Fifty-one individuals completed all 4 evaluations. Results: The hemoglobin concentration decreased significantly throughout the study (repeated-measures anal