Extending the models for iron and sulfur oxidation in the extreme Acidophile Acidithiobacillus ferrooxidans
Author
dc.contributor.author
Quatrini, Raquel
Author
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Appia-Ayme, Corinne
Author
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Denis, Yann
Author
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Jedlicki,
Author
dc.contributor.author
Holmes, David S.
Author
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Bonnefoy, Violaine
Admission date
dc.date.accessioned
2019-03-11T12:58:19Z
Available date
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2019-03-11T12:58:19Z
Publication date
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2009
Cita de ítem
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BMC Genomics, Volumen 10,
Identifier
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14712164
Identifier
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10.1186/1471-2164-10-394
Identifier
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https://repositorio.uchile.cl/handle/2250/164870
Abstract
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Background: Acidithiobacillus ferrooxidans gains energy from the oxidation of ferrous iron and various reduced inorganic sulfur compounds at very acidic pH. Although an initial model for the electron pathways involved in iron oxidation has been developed, much less is known about the sulfur oxidation in this microorganism. In addition, what has been reported for both iron and sulfur oxidation has been derived from different A. ferrooxidans strains, some of which have not been phylogenetically characterized and some have been shown to be mixed cultures. It is necessary to provide models of iron and sulfur oxidation pathways within one strain of A. ferrooxidans in order to comprehend the full metabolic potential of the pangenome of the genus. Results: Bioinformatic-based metabolic reconstruction supported by microarray transcript profiling and quantitative RT-PCR analysis predicts the involvement of a number of novel genes involved in iron and sulfur oxidation in A. ferrooxidans ATCC2327