Spina bifida occulta associated with environmental arsenic exposure in a prehispanic sample from northern Chile Evaluación de la frecuencia de espina bífida oculta y su posible relación con el arsénico ambiental en una muestra prehispánica de la Quebrada
Author
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Silva-Pinto, Verónica
Author
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Arriaza, Bernardo
Author
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Standen, Vivien
Admission date
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2019-03-11T13:00:05Z
Available date
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2019-03-11T13:00:05Z
Publication date
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2010
Cita de ítem
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Revista Medica de Chile, Volumen 138, Issue 4, 2018, Pages 461-469
Identifier
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00349887
Identifier
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07176163
Identifier
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https://repositorio.uchile.cl/handle/2250/165028
Abstract
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Background: The Camarones River Valley, located in the extreme north of Chile, is characterized by high environmental arsenic levels and an arid desert. It has been inhabited by humans for the past 7,000 years. Evidence exists for chronic arsenic poisoning in both prehispanic and present populations residing in the area. Chronic arsenic exposure causes multi-systemic problems and can induce congenital malformations, in particular neural tube development defects such as spina bifida. Aim: To study the prevalence of spina bifida among prehispanic mummies of the area. Material and Methods: One-hundred and twenty prehistoric adult individuals were analyzed for evidence of spina bifida occulta of the sacrum in skeletal samples from the sites of Camarones 8, Camarones 9, Azapa 140 and Lluta 54, held in repository at the Museo Universidad de Tarapacá de Arica-San Miguel de Azapa. A diagnosis was considered positive when at least S1, S2 or S3 were affected. As controls, mummies of individuals
Spina bifida occulta associated with environmental arsenic exposure in a prehispanic sample from northern Chile Evaluación de la frecuencia de espina bífida oculta y su posible relación con el arsénico ambiental en una muestra prehispánica de la Quebrada