Hypovitaminosis D in pediatric patients on renal replacement therapy Hipovitaminosis D en pacientes pediátricos en terapia de sustitución renal
Author
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Delucchi Bicocchi, María Angela
Author
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Alarcón, Claudia
Author
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Cano Schuffeneger, Francisco
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Lillo, Ana María
Author
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Guerrero, José Luis
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Azócar Pruyas, Marta
Author
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Abarzúa, Carolina
Author
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Muñoz, María José
Author
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Iñíguez Vila, Germán
Admission date
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2019-03-11T13:01:51Z
Available date
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2019-03-11T13:01:51Z
Publication date
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2011
Cita de ítem
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Revista Medica de Chile, Volumen 139, Issue 3, 2018, Pages 334-339
Identifier
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00349887
Identifier
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07176163
Identifier
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10.4067/S0034-98872011000300008
Identifier
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https://repositorio.uchile.cl/handle/2250/165293
Abstract
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Background: Hypovitaminosis D has a high prevalence among patients with chronic kidney disease (CKD). Aim: To determine the prevalence of 25 hydroxy vitamin D (25(OH) D) insufficiency and deficiency in pediatric patients on dialysis and kidney transplantation. Material and Methods: Serum calcium and phosphorus, parathormone (PTH), alkaline phosphatases and 25 (OH)D were measured in 13 children on hemodialysis (HD), 18 on peritoneal dialysis (PD) and 53 that received an allograft (Tx), aged 9.8 ± 4.6 years (51% females). Results: Fifty four percent of patients had height Z score less than -1.88. Patients on HD had the lowest values. The average time of replacement therapy was 2.9 ± 2.8 years. Mean 25(OH)D levels in all was 18.7 ± 10.7ng/ml (HD: 21 ± 16.8, PD: 18.9 ± 8.5, Tx: 18.1 ± 9.72 ng/ml). Eighty eight percent of patients had levels below 30 ng/ml. Mean of serum calcium was 9.5 ± 0.64 mg/dl, serum phosphorus 5.03 ± 1.02 mg/dl, calcium-phosphorus product 48 ± 11.8 mg/dl and alkaline