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Authordc.contributor.authorAlcaíno Gálvez, Hernán Alejandro 
Authordc.contributor.authorGreig, Douglas 
Authordc.contributor.authorCastro, Pablo 
Authordc.contributor.authorVerdejo, Hugo 
Authordc.contributor.authorMellado, Rosemarie 
Authordc.contributor.authorGarcía Nannig, Lorena 
Authordc.contributor.authorDíaz Araya, Guillermo 
Authordc.contributor.authorQuiroga, Clara 
Authordc.contributor.authorChiong Lay, Mario 
Authordc.contributor.authorLavandero González, Sergio 
Cita de ítemdc.identifier.citationRevista Medica de Chile, Volumen 139, Issue 4, 2018, Pages 505-515
Abstractdc.description.abstractComplications and mortality of heart failure are high, despite the availability of several forms of treatment. Uric acid, the end product of purine metabolism would actively participate in the pathophysiology of heart failure. However, there is no consensus about its action in cardiovascular disease. Serum uric acid would have a protective antioxidant activity. This action could help to reduce or counteract the processes that cause or appear as a result of heart failure. However, these protective properties would vanish in the intracellular environment or in highly hydrophobic areas such as atherosclerotic plaques and adipose tissue. This review discusses the paradoxical action of uric acid in the pathophysiology of heart failure. © 2011 Sociedad Médica de Santiago.
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceRevista Medica de Chile
Keywordsdc.subjectHeart failure
Keywordsdc.subjectOxidative stress
Keywordsdc.subjectUric acid
Títulodc.titleThe role of uric acid in heart failure Ácido úrico: Una molécula con acciones paradójicas en la insuficiencia cardiaca
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile