Possible association between mycobacterium avium subsp paratuberculosis infection and crohn's disease Mycobacterium avium subsp paratuberculosis y enfermedad de crohn: Evidencias de una zoonosis
Author
dc.contributor.author
Patricio Retamal, M.
Author
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Caroll Beltrán, M.
Author
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Pedro Abalos, P.
Author
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Rodrigo Quera, P.
Author
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Marcela Hermoso, R.
Admission date
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2019-03-11T13:02:57Z
Available date
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2019-03-11T13:02:57Z
Publication date
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2011
Cita de ítem
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Revista Medica de Chile, Volumen 139, Issue 6, 2018, Pages 794-801
Identifier
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00349887
Identifier
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07176163
Identifier
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10.4067/S0034-98872011000600015
Identifier
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https://repositorio.uchile.cl/handle/2250/165409
Abstract
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Paratuberculosis is a chronic intestinal disease of animals caused by Mycobacterium avium subsp. paratuberculosis (MAP), which has some pathological features similar to Crohn's disease (CD) in humans. The presence of MAP in food for human consumption and in affected tissues of patients with CD has been detected. Therefore, a causal association between this microorganism and the disease in humans, has been postulated. However, several related studies have failed to confirm this hypothesis and the scientific acceptance of MAP as a zoonotic agent remains controversial. This review presents the main findings related to this issue, contrasting evidences for and against an association between MAP and CD. The need to promote national studies focusing on this area is suggested.
Possible association between mycobacterium avium subsp paratuberculosis infection and crohn's disease Mycobacterium avium subsp paratuberculosis y enfermedad de crohn: Evidencias de una zoonosis