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Authordc.contributor.authorDelucchi Bicocchi, María Angela 
Authordc.contributor.authorValenzuela, Marcela 
Authordc.contributor.authorLillo, Ana M. 
Authordc.contributor.authorGuerrero, Jose Luis 
Authordc.contributor.authorCano Schuffeneger, Francisco 
Authordc.contributor.authorAzócar Pruyas, Marta 
Authordc.contributor.authorZambrano, Pedro 
Authordc.contributor.authorSalas, Paulina 
Authordc.contributor.authorPinto, Viola 
Authordc.contributor.authorFerrario, Mario 
Authordc.contributor.authorSánchez Rodríguez, Jorge E. 
Authordc.contributor.authorCavada Chacón, Gabriel 
Admission datedc.date.accessioned2019-03-11T13:02:59Z
Available datedc.date.available2019-03-11T13:02:59Z
Publication datedc.date.issued2011
Cita de ítemdc.identifier.citationPediatric Nephrology, Volumen 26, Issue 12, 2018, Pages 2235-2244
Identifierdc.identifier.issn0931041X
Identifierdc.identifier.issn1432198X
Identifierdc.identifier.other10.1007/s00467-011-1934-6
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/165423
Abstractdc.description.abstractThis prospective, comparative trial investigated the impact on mean change in height standard deviation score (SDS), acute rejection rate, and renal function of early steroid withdrawal in 96 recipients with 5 years of follow-up. Recipients under basiliximab induction and steroid withdrawal (SW: TAC/MMF; n=55) were compared with a matched steroid control group (SC: TAC/MMF/STEROID, n=41). SW received steroids until Day 6, SC decreased to 10 mg/m 2 within 2 months post-transplant. Five years after SW, the longitudinal growth (SDS) gain was 1.4±0.4 vs. 1.1±0.3 for SC group (p<0.02). Height benefits in prepubertal and pubertal status in both groups were demonstrated in the delta growth trends (mixed model; p<0.01). Biopsy-proven acute rejection in SW was 11% and 17.5%, SC (p: ns). Mean eGFR (ml/min/1.73 m 2) at 5 years post-transplant was SW 80.6±27.8 vs. 82.6±25.1 for SC (p: ns). The death-censored graft survival rate at 1 and 5 years was 99 and 90% for SW; 98 and 96% for SC (p = ns). PT
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourcePediatric Nephrology
Keywordsdc.subjectImmunosuppressive treatment
Keywordsdc.subjectPediatric kidney transplantation
Keywordsdc.subjectSteroid withdrawal
Títulodc.titleEarly steroid withdrawal in pediatric renal transplant: Five years of follow-up
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile