Short-term antibiotic prophylaxis versus long-term antibiotic prophylaxis in major clean-contaminated maxillofacial surgery Profilaxis antimicrobiana de corta duración versus profilaxis antimicrobiana de larga duración en cirugía maxilofacial mayor limpia
Author
dc.contributor.author
Julio Villanueva, Maffei
Author
dc.contributor.author
Ignacio Araya, Maffei
Author
dc.contributor.author
Nicolás Yanine, Maffei
Admission date
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2019-03-11T13:04:02Z
Available date
dc.date.available
2019-03-11T13:04:02Z
Publication date
dc.date.issued
2012
Cita de ítem
dc.identifier.citation
Revista Chilena de Infectologia, Volumen 29, Issue 1, 2018, Pages 14-18
Identifier
dc.identifier.issn
07161018
Identifier
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10.4067/S0716-10182012000100002
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/165597
Abstract
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Introduction: There is no consensus on the most appropriate duration of antimicrobial prophylaxis (single or multiple dose) in clean-contaminated maxillofacial surgery. Objective: To determine whether short-term antimicrobial prophylaxis is effective compared to long-term antimicrobial prophylaxis in preventing surgical site infection in clean-contaminated maxillofacial surgery. Patients and Methods: The cohort study included 527 patients. We compared the incidence of surgical site infection in two groups. One group received short-term antibiotic prophylaxis (single dose) and the other group, long-term antimicrobial prophylaxis (multiple dose). Results: The single dose group showed 5.7% of postoperative infections and the multiple-dose group, 5.9%, with an odds ratio of 0.96 (95% CI 0.44 to 2.10) p = 0.9214. Conclusion: No significant differences were found between the infection incidences in the single dose antibiotic prophylaxis group compared with the use of multiple doses.
Short-term antibiotic prophylaxis versus long-term antibiotic prophylaxis in major clean-contaminated maxillofacial surgery Profilaxis antimicrobiana de corta duración versus profilaxis antimicrobiana de larga duración en cirugía maxilofacial mayor limpia