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Authordc.contributor.authorUrzúa Salinas, Cristhian 
Authordc.contributor.authorVásquez, Darío H. 
Authordc.contributor.authorHuidobro, Andres 
Authordc.contributor.authorHernandez, Helio 
Authordc.contributor.authorAlfaro, Jorge 
Admission datedc.date.accessioned2019-03-11T13:19:40Z
Available datedc.date.available2019-03-11T13:19:40Z
Publication datedc.date.issued2012
Cita de ítemdc.identifier.citationCurrent Eye Research, Volumen 37, Issue 8, 2018, Pages 684-688
Identifierdc.identifier.issn02713683
Identifierdc.identifier.issn14602202
Identifierdc.identifier.other10.3109/02713683.2012.674609
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/165698
Abstractdc.description.abstractPurpose: To determine symptoms improvement in dry eye patients with short-term autologous serum (AS) eyedrops treatment using the standardized Ocular Surface Disease Index (OSDI) survey. Materials and methods: A double-blind randomized crossover clinical trial was conducted, comparing short-term (2 weeks) topical treatment with AS eyedrops diluted at 20% versus conventional artificial tears treatment in adult severe dry eye syndrome (DES) patients. The main outcome measure was assessment of symptoms with OSDI survey. Secondary outcomes were corneal and conjunctival fluorescein staining score of OXFORD and tear break up time (TBUT). The protocol was registered in www.clinicaltrials.gov, ID number: NCT00779987. Results: Twelve severe DES patients were included. Autologous serum treatment showed a statistically significant (p = 0.002) higher OSDI decrease (50%) versus conventional treatment (22%). There were no significant changes in objectives parameters (OXFORD and TBUT). Conclusions: S
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceCurrent Eye Research
Keywordsdc.subjectArtificial tears
Keywordsdc.subjectAutologous serum
Keywordsdc.subjectDry eye syndrome
Keywordsdc.subjectOcular surface
Keywordsdc.subjectOSDI
Títulodc.titleRandomized double-blind clinical trial of autologous serum versus artificial tears in dry eye syndrome
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile