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Authordc.contributor.authorFernández Arancibia, Virginia 
Authordc.contributor.authorTapia Opazo, Gladys 
Authordc.contributor.authorVidela Cabrera, Luis 
Cita de ítemdc.identifier.citationWorld Journal of Hepatology, Volumen 4, Issue 4, 2018, Pages 119-128
Abstractdc.description.abstractLiver preconditioning (PC), defined as an enhanced tolerance to injuring stimuli induced by previous specific maneuvers triggering beneficial functional and molecular changes, is of crucial importance in human liver transplantation and major hepatic resection. For these reasons, numerous PC strategies have been evaluated in experimental models of ischemia-reperfusion liver injury, which have not been transferred to clinical application due to side effects, toxicity and difficulties in implementation, with the exception of the controversial ischemic PC. In recent years, our group has undertaken the assessment of alternate experimental liver PC protocols that might have application in the clinical setting. These include thyroid hormone (T3), n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA), or iron, which suppressed liver damage due to the 1 h ischemia-20 h reperfusion protocol. T3, n-3 LCPUFA and iron are hormetic agents that trigger biologically beneficial effects in the low-dos
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceWorld Journal of Hepatology
Keywordsdc.subjectLiver preconditioning
Keywordsdc.subjectN-3 polyunsaturated fatty acids
Keywordsdc.subjectThyroid hormone
Títulodc.titleRecent advances in liver preconditioning: Thyroid hormone, n-3 long-chain polyunsaturated fatty acids and iron
Document typedc.typeArtículo de revista
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile